With the rapid development of veterinary industry and the wide application of biotechnology in China, especially after the outbreak of SARS in spring 2003 and the outbreak of highly pathogenic avian influenza in early 2004, the announcement number of the Ministry of Agriculture on this issue is as follows. According to the "Standards for Biosafety Management of Veterinary Laboratories" in 302, the number of reports applied for the establishment of acoustic logging-3 laboratories has increased, and the construction and maintenance of biosafety laboratories need huge financial support. How to concentrate limited funds, strengthen the construction of biosafety laboratories, and promote the emergency response capacity of animal diseases and major animal health emergencies has become our current worker. Important subject to be done. Therefore, a delegation composed of experts'laboratories of the Ministry of Agriculture visited France, Sweden, high-level biosafety laboratories and related facilities and equipment manufacturers. The survey found that many successful experiences of foreign countries in biosafety laboratory construction planning and management are of great significance in the construction of veterinary laboratories in China. The results of this survey will be published, hoping to be combined with practical application in various fields in practice.
1. Design Institute, Kripaga, Paris
Our Design Institute is a company specializing in biosafety laboratory design. More than 90% of the high-level biosafety laboratories in France are designed by the institute, including the BSL-4 Laboratory of Jean Meieu in Lyon, the BSL-3 Laboratory of Pasteur Institute and the BSL-3 Laboratory of bacterial research in the French Army.
2. Jean-jean-merrier bsl-4实验室
2. Jean-jean-merrier BSL-4 Laboratory
The laboratory covers an area of 600 square meters and costs 40 million francs, including 10 million francs for equipment and equipment and 1.9 million euros for annual operation and maintenance experiments.
实验室完全由玻璃和钢铁建造，被一致认为是“新一代P4的个”。实验室由主楼和附属楼组成，主楼为3层钢框架结构，玻璃幕墙。主楼上层为技术供应区，设有实验室、人畜供气处理系统、水电供应系统;中层为bsl-4实验室工作区，外层为圆形视觉走廊。参观者可以使用磁卡从接待区通过两扇门进入。通过观察窗，参观者可以看到实验室的不同区域。通过环形视觉走廊,进入缓冲区,包括一系列的气体在这个地区锁门(更衣间,清洁浴室,把衣服和喷雾消毒房间),所有空气锁自动联锁,毗邻门不能同时打开,通过缓冲区,输入声波测井——实验室核心区域,该区域2占地面积70 ~ 80平方米的独立实验室和1动物实验室的效用,设计原则就是把盒子放在盒子里”;下层为废物处理区、实验室设备、实验废物、污水消毒处理。附属建筑紧邻广场主楼，为2层半圆柱形金属结构附属建筑，建在另一栋建筑的顶层。它包括一个支持bsl-4实验室的低层实验室和一个用于实验室计算机的中央控制室，负责整个实验室的实验准备和中央监控。
The laboratory, built entirely of glass and steel, is universally regarded as the "first of the new generation of P4". The laboratory consists of a main building and a subsidiary building. The main building is a three-storey steel frame structure with glass curtain wall. The upper floor of the main building is a technology supply area, with laboratories, gas supply system for human and livestock, and water and electricity supply system; the middle floor is a BSL-4 laboratory working area, and the outer layer is a circular visual corridor. Visitors can use magnetic cards to enter the reception area through two doors. Through the observation window, visitors can see different areas of the laboratory. Through the circular visual corridor, enter the buffer area, including a series of gases in this area to lock the door (dressing room, clean the bathroom, clothes and spray disinfection room), all air locks are automatically interlocked, adjacent doors can not be opened at the same time, through the buffer zone, the input acoustic logging - laboratory core area, the area 2 covers an area of 70 to 80 square meters of independent laboratory and 1 animal laboratory effectiveness. The design principle is to put boxes in boxes; the lower level is waste disposal area, laboratory equipment, experimental waste, sewage disinfection treatment. The adjacent building is adjacent to the main building of the square. It is a two-story semi-cylindrical metal structure adjacent building. It is built on the top floor of another building. It consists of a low-level laboratory supporting the BSL-4 laboratory and a central control room for laboratory computers. It is responsible for the laboratory preparation and central monitoring.
3. Paris Delta Protective Clothing Factory
The company is a protective clothing manufacturer of Encyclopedia-Dallows Group, the world's first protective products production and marketing group, long engaged in research and production of radiation protective clothing. At present, the annual output of 100,000 sets, widely used in chemical, pharmaceutical, biological and other fields of protective clothing and supplies.
Among them, the positive pressure protective clothing with life support system produced by the company is the most unique, including the positive pressure protective clothing matched with the BSL-4 gas supply system, and the portable oxygen supply device which can be used for field sampling.